Rebecca De Mornay
Natalie 'Mother' Koffin

Jaime King
Beth Sohapi

Frank Grillo
Daniel Sohapi

Patrick John Flueger
Izaak 'Ike' Koffin

Warren Kole
Addley Koffin

Deborah Ann Woll
Lydia Koffin

Matt O'Leary
Jonathan 'Johnny' Koffin

Briana Evigan
Annette Langston

Shawn Ashmore
George Barnum

Kandyse McClure
Gina Jackson

Lyriq Bent
Treshawn Jackson

Lisa Marcos
Julie Ross

Jessie Rusu
Melissa McGuire

Tony Nappo
Dave Lowe

Jason Wishnowski
Charlie Kaufman

A. J. Cook
Vicky Rice

Alexa PenaVega
Jenna Luther

J. LaRose
Hospital Security Guard

Jennifer Hupe
Young Nurse

Mike O'Brien
Officer Skay

Will Woytowich
Paramedic

Omar Alex Khan
Surgeon

Andrew Bryniarski
Quincy, Sanitation Worker #2

Joanne Rodriguez
Dry Cleaner (uncredited)