Penelope Ann Miller
Dr. Margo Green

Tom Sizemore
Lt. Vincent D'Agosta

Linda Hunt
Dr. Ann Cuthbert

James Whitmore
Dr. Albert Frock

Clayton Rohner
Det. Hollingsworth

Chi Muoi Lo
Dr. Greg Lee

Robert Lesser
Mayor Robert Owen

Diane Robin
The Mayor's Wife

Lewis van Bergen
John Whitney

Constance Towers
Mrs. Harriet Blaisedale

Francis X. McCarthy
Mr. George Blaisedale

Audra Lindley
Dr. Matilda Zwiezic

John Kapelos
McNally

Tico Wells
Bailey

Mike Bacarella
Bradley

Gene Davis
Martini

David Proval
Guard Johnson

Jophery C. Brown
Guard Frederick Ford

Don Harvey
Spota

Santos Morales
Capt. Borne

Ralph Seymour
Sergeant

Lyn Alicia Henderson
Perri Masai

Brian Steele
Kothoga

Amanda Ingber
Donna

Eddie Jemison
Museum Worker

Kurt Naebig
Police Officer

Ken Magee
Coroner's Assistant

Aaron Lustig
Dr. Brown

Ron Cummins
Dr. Gross

Gary A. Hecker
Kothoga (voice)

Craig Hosking
Helicopter Pilot

Dana Kristen Vahle
Helicopter Pilot

Dick Warlock
Policeman (uncredited)