Rainn Wilson
Randy

Lil Rel Howery
Mike

Aimee Carrero
Jessica

Yvette Nicole Brown
Shanice

Rob Riggle
Dr. Serano

Page Kennedy
Officer Taggert

Xolo Mariduena
Rookie

Eric Jungmann
Nurse Chad

Ayesha Harris
Kim

Luka Jones
Motorcycle Matt

Andy Milder
Bruce

Cameron Fuller
Jimmy

Liam Oh
Chip (uncredited)

Michael Monks
Officer White

Patrick Pianezza
Paramedic Patrick

Rafael Castillo
Charlie (Mr. President)

Peter Holden
Angry White Guy

Melissa Bailey
Charge Nurse

Treisa Gary
Nurse Ruth

Sierra Swartz
Jenna - Sorority Girl

Juan Pacheco
Baseball Coach

Omar Leyva
Vicente's Uncle

Adam Mondschein
Drunk Rocky