Luke Wilson
Mitch

Will Ferrell
Frank

Vince Vaughn
Beanie

Jeremy Piven
Pritchard

Ellen Pompeo
Nicole

Juliette Lewis
Heidi

Jerod Mixon
Weensie

Leah Remini
Lara

Perrey Reeves
Marissa

Patrick Cranshaw
Blue

Craig Kilborn
Mark

Elisha Cuthbert
Darcie

Seann William Scott
Peppers

Rick Gonzalez
Spanish

Matt Walsh
Walsh

Artie Lange
Booker

Patrick Fischler
Michael

Sara Tanaka
Megan

Harve Presnell
Mr. Springbrook

Katherine Ellis
Amy

Phe Caplan
Julie

Sarah Shahi
Erica

Kristen Kerr
Lisa

Dan Finnerty
Wedding Singer

Gregory Alan Williams
Therapist

Ashley Jones
Caterer

Bryan Callen
Waiter

James Carville
Himself

Todd Phillips
Gang Bang Guy

Stuart Cornfeld
Taxi Driver

Corinne Kingsbury
Jenny

Lisa Donatz
Jeanie

David Moreland
Convention Speaker

Rachel Winfree
Archer's Wife

Nathalie Fay
Mindy

Kristina Hughes
Naked Woman

Nicholas Hosking
Naked Man

Noel Gugliemi
Student #1

Robert Baker
Student #2

Arthur Taxier
Professor

Snoop Dogg
Self

Warren G
Self

Bishop Don Magic Juan
Self

Kokane
Self

Matthew Carey
Hatch

Simon Helberg
Jerry

Eddie Pepitone
Archer

Rob Corddry
Warren

Raymond Ma
Mr. Ma

Jesse Heiman
Budnick

Patrick J. Adams
Patch

Jake Jarvi
Jarvi

Ellen Cleghorne
Trustee (uncredited)

Andy Dick
Barry (uncredited)

Terry O'Quinn
Goldberg (uncredited)

Allen Bloomfield
Airplane Ticket Buyer (uncredited)

Katie Carlin
Wedding Guest (uncredited)