Meryl Streep
Karen Silkwood

Kurt Russell
Drew Stephens

Cher
Dolly Pelliker

Craig T. Nelson
Winston

Fred Ward
Morgan

Diana Scarwid
Angela

Ron Silver
Paul Stone

Charles Hallahan
Earl Lapin

Josef Sommer
Max Richter

Sudie Bond
Thelma Rice

Henderson Forsythe
Quincy Bissell

E. Katherine Kerr
Gilda Schultz

Bruce McGill
Mace Hurley

David Strathairn
Wesley

J.C. Quinn
Curtis Schultz

Kent Broadhurst
Carl

Richard Hamilton
Georgie

Les Lannom
Jimmy

M. Emmet Walsh
Walt Yarborough

Graham Jarvis
Doctor at Union Meeting

James Rebhorn
Los Alamos Doctor

Bill Cobbs
Man in Lunchroom

Ray Baker
Pete Dawson

Will Patton
Joe

Tess Harper
Linda Dawson

Anthony Heald
2nd Doctor at Union Meeting

Gary Grubbs
Randy Fox