Paul Rudd
Jeff Reigert

Adam Brody
Stephen Montgomery

Jon Hamm
Chris Knarl

Winona Ryder
Kelly La Fonda

Ken Marino
Glenn Richie

Mather Zickel
Louis La Fonda

Ali Marsh
George Reardon

Ron Silver
Fielding Barnes

Michael Paul
Harlan Swallow

Jason Antoon
Salazar 'Fred' McBairn

Andrea Rosen
Polly 'Carol' Samuels

Chris Wylde
Kevin Lipworth

Siri Baruc
Natalie Freyberg

Reed Birney
Jim Stansel

Erica Oyama
Breem Benson

Famke Janssen
Gretchen Reigert

Gretchen Mol
Gloria Jennings

A.D. Miles
Oliver Jennings

Jason Sudeikis
Tony Contiella

Paco Mauri
Alfonso Zavata

Justin Theroux
Jesus H. Christ

Tommy Nelson
Noah Jennings

Liev Schreiber
Ray Johnson

Zak Orth
Barge Michaelson

Nina Hellman
Nancy Hellman

Beth Dover
Sheila Contiella

Matt Ballard
Greg Splenda

Novella Nelson
Sophia Jackson

Scott Sowers
Barry Noodle

Michael Mulheren
Carvin 'Big Buster' Waggle

Jessica Alba
Liz Anne Blazer

Kevin Allison
Stanley Jaffe

Kerri Kenney
Bernice Jaffe

Cedric Sanders
Greg Jaffe

Arlen Escarpeta
Todd Jaffe

Oliver Platt
Marc Jacobson

David Wain
Abe Grossman / Cartoon Voices

Thomas Lennon
Scotty Pale

Zandy Hartig
Sally Johnson / Callie Mardino / Cartoon Voices

Joe Lo Truglio
Paul Mardino

Charlie McDermott
Jake Johnson

Zach Page
Loofie Lavinsky

Janeane Garofalo
Beth Soden

Rob Corddry
Duane Rosenblum

Antonio Zavala Kugler
Carlos Lopez 'Gonzalez' Banderas

Michael Ian Black
Prison Guard Jamberg Saivon

Rashida Jones
Hostess Rebecca Fornier

Michael Showalter
Police Lt. Flarn Bleern

Joe Passaro
Clovis Handleman

Jerry Grayson
Junkie Floyd Congril Dillon

John Tormey
Junkie Jerry Park

H. Jon Benjamin
Lying Rhino (voice)

Jonathan Stern
Cartoon Voices / Naked Guy

Peter Salett
Lying Rhino Body

Bobby Cannavale
Marty McBride

Robert Ben Garant
Self

John Patrick Barry
Naked Guy

Seth Herzog
Naked Guy

Peter Moore
Naked Guy