Jean Claude Ricquebourg
Christopher Columbus

José Antonio Lorente
Self - Geneticist / Narrator (voice)

Marcial Castro
Self - Historian

Esther Martín
Self - Journalist

Ainhoa del Castillo
Self - Colón ADN Coordinator

Regis Francisco López
Self - Journalist

Carlos Bayarri
Self - Museo Pickman Curator

Juan Manuel Martín
Self - Edaphology Professor

Rafael Delgado
Self - Edaphology Professor

Vanessa Gómez
Self - Journalist

Alfonso Sanz
Self - Castilian Theory Promoter

Fernando Branco
Self - 1st Portuguese Theory Promoter

José Matos Silva
Self - 2nd Portuguese Theory Promoter

Eduardo Esteban
Self - Galician Theory Promoter

Inmaculada Alemán
Self - Forensic Anthropologist

José Aguiño
Self - Restorer

Gabriel Martorell
Self - Balearic Theory Promoter

José María Ercilla
Self - Agote Theory Promoter

Francesc Albardaner
Self - Jewish Theory Promoter

Cristina Gutiérrez González
Queen Isabel

Ángel González Álvarez
King Fernando

Juan Frías Sanz
Prince of Viana

Santiago Salgado Bellido
Diego Colón - Son

Saúl de Lucas Muñoz
Hernando Colón

Pepe Pereira
Diego Colón - Brother

Cristina Vargas Carracedo
Margalida Colom

Nerea García Martín
Filipa Moniz

Javier García Botello
Young Columbus

Adrián Casado Cuadrado
Child Columbus (Medina)

Martín Martín Hernández
Child Columbus (Palos)

Carlos Fernández Rodríguez
Bartolomé Colón

Rafael Martínez Macías
Juan de la Cosa

José Luis de la Fuente
King of Portugal

Juan José García Galindo
Luis de Santángel

Vidal López Rojo
Duke of Medinaceli

Juan José Domínguez Monge
Francisco de Bobadilla

Laura Cuadrado Conde
Columbus' Mother (Medina)

Francisco Javier Romero
Columbus' Father

Antonio Ortiz García
Priest #1

Santiago Herranz Alberquilla
Priest #2

Juan José Rodríguez
Monk #1

Samuel Belaúnde
Monk #2

Máximo Gallego
Alonso Sánchez de Huelva

Antonio Barrera
Jewish Man

Monserrat Antiñolo
Jewish Woman

Azucena Montalvo
Secretary

Raúl Sandoval
Man on Phone

Lorenzo Milá
Self - Anchorman (archive footage)