Meryl Streep
Rachel

Jack Nicholson
Mark

Jeff Daniels
Richard

Maureen Stapleton
Vera

Stockard Channing
Julie

Richard Masur
Arthur

Catherine O'Hara
Betty

Steven Hill
Rachel's Father

Miloš Forman
Dimitri

Mamie Gummer
Annie

Karen Akers
Thelma Rice

Anna Maria Horsford
Della

Ron McLarty
Detective O'Brien

Kenneth Welsh
Dr. Appel

Kevin Spacey
Subway Thief

Mercedes Ruehl
Eve

Joanna Gleason
Diana

Jack Gilpin
Ellis

Christian Clemenson
Sidney

John Wood
British Moderator

Yakov Smirnoff
Contractor Laszlo

Caroline Aaron
Judith

Lela Ivey
Hairdresser

Tracey Jackson
Hairdresser's Friend

Angela Pietropinto
Hospital Receptionist

Susan Forristal
Magazine Colleague

Dana Ivey
Wedding Speaker

John Rothman
Jonathan Rice

Salem Ludwig
Judge

May Pang
Dinner Party Guest

Ari M. Roussimoff
Workman

Natasha Lyonne
Rachel's Niece (uncredited)

Carlotta Schock
Dinner Guest (uncredited)

Tony Shalhoub
Airplane Passenger (uncredited)