William Powell
Nick Charles

Myrna Loy
Nora Charles

Lucile Watson
Mrs. Marta Charles

Gloria DeHaven
Laura Belle Ronson

Anne Revere
Crazy Mary

Helen Vinson
Helena Draque

Harry Davenport
Dr. Bertram Charles

Leon Ames
Edgar Draque

Donald Meek
Willie Crump

Edward Brophy
Brogan

Lloyd Corrigan
Dr. Bruce Clayworth

Anita Sharp-Bolster
Hilda

Donald MacBride
Police Chief MacGregor

Morris Ankrum
Willoughby Peavy

Nora Cecil
Miss Peavy

Minor Watson
Sam Ronson

Irving Bacon
Tom

Virginia Sale
Tom's Wife

Joseph Crehan
Clancy - Policeman at Railroad Station (uncredited)

Tom Dugan
Studs Lonnegan (uncredited)

Wally Cassell
Bill Burns (uncredited)

Edward Gargan
Mickey Finnegan (uncredited)

Rex Evans
Fat Man in Train Passageway (uncredited)

Charles Halton
R.T. Tatum (uncredited)

Paul Langton
Tom Clayworth (uncredited)

Etta McDaniel
Ronson's Maid (uncredited)

Clarence Muse
Porter on Train (uncredited)

Robert Emmett O'Connor
Baggage Attendant on Train (uncredited)

Garry Owen
Pool Player (uncredited)

Jack Perry
Man in Pool Hall Brawl (uncredited)

William H. O'Brien
Train Passenger (uncredited)

Oliver Blake
Reporter (uncredited)

Sam Flint
Hotel Clerk (uncredited)

Harry Hayden
Train Conductor (uncredited)

Mitchell Lewis
Third Man Outside Barber Shop(uncredited)