Johnny Depp
Dr. Will Caster

Rebecca Hall
Evelyn Caster

Paul Bettany
Max Waters

Cillian Murphy
Agent Donald Buchanan

Kate Mara
Bree

Cole Hauser
Colonel Stevens

Morgan Freeman
Joseph Tagger

Clifton Collins Jr.
Martin

Cory Hardrict
Joel Edmund

Falk Hentschel
Bob

Josh Stewart
Paul

Luce Rains
Roger

Fernando Chien
Heng

Xander Berkeley
Dr. Thomas Casey

Lukas Haas
James Thomas

Wallace Langham
Dr. Strauss

James Burnett
Meth Head #1

Sam Quinn
Meth Head #2

Chris Gartin
Tech Conference Coordinator

Olivia Taylor Dudley
Groupie

Abe Bueno-Jallad
RIFT Hacker

Nancy Jeris
BDC Servant

Dylan Kenin
FBI Agent

Chad Brummett
Solar Field Worker

Antonio Del Prete
Will In Hybrid

Kristen DeVore Rakes
MIT Programmer

Seth Adkins
Miserable Student

Kendra Tuthill
Townswoman (uncredited)

Dennis Keiffer
Hybrid Soldier (uncredited)

Elon Musk
Elon Musk (uncredited)