Elizabeth Banks
Meghan

James Marsden
Gordon

Gillian Jacobs
Rose

Sarah Wright
Denise

Ethan Suplee
Officer Dave

Bill Burr
Officer Walter

Ken Davitian
Cab Driver

Lawrence Gilliard Jr.
Scrilla

Alphonso McAuley
Pookie

Da'Vone McDonald
Hulk

Eric Etebari
Biker Boy

Oliver Hudson
Kyle

Jacob Timothy Manown
Kid with Bike

Carol Mansell
Charon

Bryan Callen
Dealer

Tig Notaro
Impound Woman

Willie Garson
Dan Karlin

Chris Conner
Tommy

Liz Carey
Jordan

Brandon Scott
Josh

Ian Roberts
Main Network Executive

Kevin Nealon
Chopper Steve

Dan Callahan
Young Producer

Jerry Minor
Lt. Drier

Niecy Nash-Betts
Bus Driver

Eve Brenner
Old Lady

P.J. Byrne
Moshe

Tonja Kahlens
Ginger the Hooker

John Farley
John

Richard Cabral
Gang Member

Geoffrey Rivas
Store Owner

Cindera Che
Madame

Carolina Monte Rosa
Kyle's Girlfriend

Sam Upton
Cop

Vic Chao
Shift Captain

Donnie Smith
Biker Boy Crew #1

David Bortolucci
Duke

Nilla Elizabeth Watkins
Hooker

Amanda Young
Julie

Gillian Vigman
Female Blooper Anchor #1

Justin Smith
Male Blooper Anchor #1

Ann Reilly
Female Blooper Anchor #2

Cooper Thornton
Male Blooper Anchor #2

Emily Wagner
Female Blooper Anchor #1

Elizabeth Chomko
Female Blooper Anchor #5

Rocky Russo
Male Blooper Reporter #1

Keeshan Giles
Male Blooper Reporter #2

Andrew Friedman
Male Blooper Reporter #3

Steven Brill
Male Blooper Lawyer

Jesse Erwin
Prankster

Mark Cirillo
Charlie (uncredited)

Gary Sievers
Hasidic Jew (uncredited)

Maggie Wagner
News Station Executive (uncredited)