William Powell
Steve Ireland

Myrna Loy
Susan Ireland

Gail Patrick
Isobel Kimble Grayson

Jack Carson
Ward Willoughby

Florence Bates
Mrs. Cooper

Sidney Blackmer
Lawyer George Renny

Sig Ruman
Dr. Wuthering

Vladimir Sokoloff
Dr. David Klugle

Donald MacBride
'Pinky' Grayson

Sara Haden
Miss Cecilia Landis

Kathleen Lockhart
Mrs. Bristol

Fern Emmett
Martha - Ireland's Maid

Joseph Crehan
Judge

George Meeker
Lawyer DeWest

Clarence Muse
Robert - Hat Check Man at Party

Elisha Cook Jr.
Joe (elevator operator)

Barbara Bedford
Renny's Secretary (uncredited)

Aldrich Bowker
Jimmy - the Doorman (uncredited)

Edward Hearn
Policeman (uncredited)

George Irving
Sanity Hearing Doctor (uncredited)

May McAvoy
Sanity Hearing Secretary (uncredited)

Ian Wolfe
Sanity Hearing Doctor (uncredited)

Wanda Perry
Party Guest (uncredited)

Joan Barclay
Telephone Operator (uncredited)

Wade Boteler
Head Private Investigator (uncredited)

Francis X. Bushman Jr.
Uniformed Sanitarium Guard (uncredited)

Naomi Childers
Party Guest (uncredited)

Sayre Dearing
Party Guest (uncredited)

Jay Eaton
Party Guest Getting Rake (uncredited)

Pat Gleason
Philadelphia Private Investigator (uncredited)

Roy Gordon
Sanity Hearing Doctor (uncredited)

Jesse Graves
Bristol's Butler (uncredited)

George Guhl
First Taxi Driver (uncredited)

Mahlon Hamilton
Party Guest (uncredited)

Selmer Jackson
Doctor at Susan's Apartment (uncredited)

George Magrill
Sanitarium Guard (uncredited)

Philo McCullough
Cleveland Private Investigator (uncredited)

James Millican
Miami Private Investigator (uncredited)

Jack Mulhall
Court Clerk (uncredited)

Spec O'Donnell
Anniversary Singer (uncredited)

Broderick O'Farrell
Party Guest (uncredited)

Edward Peil Sr.
Sun Valley Private Investigator (uncredited)

Lee Phelps
Uniformed Sanitarium Guard (uncredited)

James Pierce
San Francisco Private Investigator (uncredited)

Bert Roach
Front Desk Clerk (uncredited)

Larry Steers
Party Guest Whose Hat is Floating (uncredited)

Harry Strang
Police Sgt. Payson (uncredited)

William Tannen
Sanitarium Attendant (uncredited)

Edward Van Sloan
Sanity Hearing Doctor (uncredited)

Emmett Vogan
Doctor at Susan's Apartment (uncredited)

Douglas Wood
Sanity Hearing Doctor (uncredited)