Ricky Gervais
Mark Bellison

Jennifer Garner
Anna McDoogles

Louis C.K.
Greg Kleinschmidt

Rob Lowe
Brad Kessler

Jonah Hill
Frank Fawcett

Jeffrey Tambor
Anthony James

Fionnula Flanagan
Martha Bellison

Tina Fey
Shelley Bailey

Donna Sorbello
Anna's Mother

Jason Bateman
Doctor

Philip Seymour Hoffman
Jim the Bartender

Jimmi Simpson
Bob

Stephanie March
Blonde

Ruben Santiago-Hudson
Landlord

John Hodgman
Wedding Overseer

Nate Corddry
News Reporter

Christopher Guest
Nathan Goldfrappe

Alton Fitzgerald White
Angelo Badsmith

Edward Norton
Cop

Shaun Williamson
Richard Bellison

Stephen Merchant
Man at the Door

Michael Patrick Gough
Homeless Man

Ashlie Atkinson
Bank Teller

Lisa Paige Robinson
Arguing Girlfriend

Martin Starr
Waiter #1

Tate Ellington
Waiter #2

Arnie Burton
Waiter at Fancy Restaurant

Bobby Moynihan
Assistant

Cole Jensen
Short Fat Brian

Conner Rayburn
Son

Roz Ryan
Nurse #1

Nada Despotovich
Nurse #2

Jared Voss
Person #1

Elena Wohl
Person #3

Matthew Robinson
Person #4

Joe Stapleton
Man #8

Lance Norris
Man #1

Eric André
Man #4

Gene Amoroso
Man #5

Armen Garo
Man #6

Dreama Walker
Receptionist

Rachel Harker
Woman in Business Suit

Toni Saladna
Cocktail Waitress

Ken Cheeseman
Shouting Man

David Pittu
Tour Guide

Danielle Perry
Hostess in La Bonisera

Celeste Oliva
Secretary

Alison Quinn
Talking Head Woman

John Franchi
Casino Gambler (uncredited)