Jennifer Lawrence
Joy

Robert De Niro
Rudy

Bradley Cooper
Neil Walker

Edgar Ramírez
Tony

Diane Ladd
Mimi

Virginia Madsen
Terry

Isabella Rossellini
Trudy

Dascha Polanco
Jackie

Elisabeth Röhm
Peggy

Susan Lucci
Danica

Maurice Benard
Ridge

Donna Mills
Priscilla

Jimmy Jean-Louis
Toussaint

Ken Howard
Mop Executive

Ray De La Paz
Tony's Father

John Enos III
Roderick

Marianne Leone Cooper
Sharon

Melissa Rivers
Joan Rivers

Drena De Niro
Cindy

Isabella Crovetti
Young Joy

Emily Nuñez
Young Jackie

Madison Wolfe
Young Peggy

Aundrea Gadsby
Cristy 5 Years Old

Gia Gadsby
Cristy 5 Years Old

Tomas Elizondo
Tommy 3 Years Old

Zeke Elizondo
Tommy 3 Years Old

Lori McCoy-Bell
Angry Airline Customer

Luisa Maria Badaracco
Susan

Jamell Washington
Airline Customer Service Clerk

Johnnie McQuarley
Andre

Mateo Gómez
Latin Priest

Marcela Jaramillo
Eucaria

Melissa McMeekin
Parking Lot Woman

Erica McDermott
Parking Lot Woman

Carla Antonino
Parking Lot Woman

Michele Egerton
Parking Lot Woman

Marianne Bayard
Angela

Fiore Leo
Angela's Brother

Steven DeMarco
Angela's Brother

Damien Di Paola
Marv Brickman

Patsy Meck
Patsy

Dale Place
Boardroom Rep

Thomas Matthews
Thomas

Matthew Russell
Roger from Wardrobe

Bates Wilder
Todd

Paul Herman
Rifle Man

Christy Scott Cashman
Sarina Kimball

Colleen Camp
Lori

Patrick Pitu
Eerie Fabri-Pac Guy

Michael DeMello
Gregory

Ken Cheeseman
Gerhardt

Naheem Garcia
Police Officer

Bill Thorpe
Dallas Man

Barry Primus
Rudy's Attorney

Eliana Adise
Teen Cristy

Calidore Robinson
Teen Tommy

Jasmine Brooke White
Young Memphis Woman

Susan Garfield
Wedding Guest (uncredited)