John Turturro
Barton Fink

John Goodman
Charlie Meadows

Judy Davis
Audrey Taylor

Michael Lerner
Jack Lipnick

John Mahoney
W.P. Mayhew

Tony Shalhoub
Ben Geisler

Jon Polito
Lou Breeze

Steve Buscemi
Chet

David Warrilow
Garland Stanford

Richard Portnow
Detective Mastrionotti

Christopher Murney
Detective Deutsch

I.M. Hobson
Derek

Lance Davis
Richard St. Claire

Harry Bugin
Pete

Jack Denbo
Stagehand

Max Grodénchik
Clapper Boy

Robert Beecher
Referee

Darwyn Swalve
Wrestler

Jana Marie Hupp
USO Girl

William Preston Robertson
Voice (voice)

Frances McDormand
Stage Actress (voice) (uncredited)

Bubba Dean Rambo
Banquet Dancer (uncredited)

Barry Sonnenfeld
Page Calling for Barton Fink (uncredited)

Vincent Tumeo
Dancer (uncredited)

William H. Macy
Navy Sailor (uncredited)

Joe James
Mailman (voice)(uncredited)