Snoop Dogg
Major LeGrande Bushe

Chase Masterson
Connie Garrison / Natasha

Dina Meyer
Female Moesha

Olivia d'Abo
Female Larrisha

Marina Sirtis
Award Show Presenter

Nana Visitor
Samantha Stamen

Michael Madsen
President Ben Dover

Jeffrey Combs
Male Larrisha

Michael Dorn
Real Robert Schmitt

Armin Shimerman
Male Moesha

Julie Warner
Female Curlisha

Nichelle Nichols
Sensei

Linda Park
Amber Earhardt

Gilbert Gottfried
LeGrande Bushe

Robert Picardo
Boris / Edgar Allan Putz

Walter Koenig
Fireman Frank

John Billingsley
Male Curlisha

Tim Russ
Unreal Robert Schmitt

Crystal Allen
Jasmine

Gary Graham
Neil Downe

Brenda Bakke
Christine Choppel

Celeste Yarnall
Celeste

Gary Lockwood
Gary

Manu Intiraymi
Durwood

Beverly Washburn
Beverly

Anthony Montgomery
Launchman

Vaughn Armstrong
Russell Sprout

BarBara Luna
Self

Kaley Victoria Rose
Laura Luzair

Brooke Newton
Ramora

Jasmine Jessica Anthony
Eileen Dover

Garrett Wang
Dr. Charles Hunter

Kevin Carlson
Captain Kirk Stillwood (voice)

Connor Trinneer
Captain Jack Youngblood

Katarina van Derham
Captain Cheryl Stillwood

Dominic Keating
Hacky

Max Grodénchik
Paramedic Yacky

Casey Biggs
Detective Dan Marr

Patti Yasutake
Dr. Beverly Krasher

McKenzie Westmore
Self

Steve Rankin
Dr. Len McCoyy

Michael Dante
Michael Dante

Jack Donner
Jack Donner

Menina Fortunato
Rose

Anne McDaniels
Anne Droid

Guy Nardulli
Apollo

Steven Scot Bono
Buzz the Pothead

Seth Austin
Harold the Herald

Sam Asghari
Self

Casper Smart
Self

Angelique Kenney
Blonde Selfie Girl

Nadia Lanfranconi
Self

Bert Rotundo
Alien