Mark Feuerstein
Larry Gaye

Jayma Mays
April Elizabeth Farnekowski

Rebecca Romijn
Sally the Flightpal

Stanley Tucci
Publishing Executive

Henry Winkler
Stanley Warner

Danny Pudi
Nathan Vignes

Patrick Warburton
Captain Bryce

Jason Alexander
Larry's Dad

Molly Shannon
Emily McCoy

Leslie Coutterand
Isabella

Griffin Gluck
Donnie

Eric Stoltz
Russ Peterson

Jessica Lowndes
Suzanne

Christopher Fitzgerald
Curtis

Taye Diggs
Rasta Cab Driver

Staci Roberts
Woman in 3B

Kenny Ellis
Rabbi

Guy Wilson
Frat Guy

Michael B. Silver
Charles Geddes

Adam Shapiro
Bob Techtronics

Ian Gomez
Captain Felder

Julie Hagerty
Elevator Flight Attendant

Marcia Gay Harden
President of the FAFAFA

Frank Gingerich
Young Larry

Allison Smith
Larry's Mom

Anthony Ruivivar
Flight School Administrator

Bob Gunton
Flight School Instructor

Pete Gardner
Flight School Doctor

Paul Zies
Beef Stew Guy

Bruno Oliver
Techtronics VP

Darius Devontaye Green
Taequan Black

John Yuan
Stuart Nevins

Matt Yuan
Johann Kaminsky

Samuel Gilbert
School Bully

Richard Riehle
Bartender

Byron McIntyre
Official

Kelly Donohue
BBQ Chicken Girl

Carlease Burke
LAX Ticket Agent

Frank Clem
Unaccompanied Miner

Jere Burns
Herb Thompkins

Rosanna Arquette
TV Anchorwoman