Nate Parker
Nat Turner

Armie Hammer
Samuel Turner

Aja Naomi King
Cherry

Jackie Earle Haley
Raymond Cobb

Penelope Ann Miller
Elizabeth Turner

Gabrielle Union
Esther

Mark Boone Junior
Reverend Zalthall

Aunjanue Ellis-Taylor
Nancy Turner

Dwight Henry
Isaac Turner

Esther Scott
Bridget Turner

Roger Guenveur Smith
Isaiah

Jeryl Prescott
Janice

Colman Domingo
Hark

Dominic Bogart
Hank Fowler

Jason Stuart
Joseph Randall

Katie Garfield
Catherine Turner

Jayson Warner Smith
Earl Fowler

Steve Coulter
General Childs

Aiden Flowers
Young John Clarke

Dane Davenport
John Clarke Turner

Chiké Okonkwo
Will

Tony Espinosa
Young Nat Turner

Chris Greene
Nelson

Kelvin Harrison, Jr.
Simon

Justin Randell Brooke
Guiles Reese

Ryan Mulkay
Jesse

Bobby Batson
Little boy

Alkoya Brunson
Young Hark

Sheila Cochran
General Child's Wife

Logan Coffey
Son

Nicole Davis
Angel (uncredited)

Shannon Edwards
Farmer (uncredited)

Brad Schmidt
Lieutenant Akers

Patrick Roper
Slave Buyer