Mila Kunis
Amy Mitchell

Kristen Bell
Kiki

Kathryn Hahn
Carla Dunkler

Christina Applegate
Gwendolyn James

Jada Pinkett Smith
Stacy

Jay Hernandez
Jessie Harkness

Clark Duke
Dale Kipler

Annie Mumolo
Vicky

Emjay Anthony
Dylan Mitchell

Oona Laurence
Jane Mitchell

David Walton
Mike Mitchell

Wendell Pierce
Principal Daryl Burr

J.J. Watt
Coach Craig

Leah McKendrick
Sharon

Lyle Brocato
Kent

Wanda Sykes
Dr. Elizabeth Karl

Cade Mansfield Cooksey
Jaxon

Ann Mahoney
Mousey Mom

Samantha Beaulieu
Tiger Mom

Yuka Takara
Nearby Mom

Jackie Tuttle
Mom Janet

Adria Tennor
Conservative Mom

Kelly Lind
Audrey

Lena Clark
Departing Mom

Amy Brassette
Drunk Mom

Donna DuPlantier
Vera

Lindsey Garrett
Intense Mom

Christina DeRosa
Heather

Shauna Rappold
Business Mom

Lara Grice
Tired Mom

Liz Elkins Newcomer
Stay at Home Mom

Carrie Lazar
Strange Mother

Nina Millin
Gina

Yan Feldman
Bartender

Jaylen Moore
Steve

David Simpson
Monotone Hipster

Turner Crumbley
Jeff

Billy Slaughter
Veterinarian

Meghan Wolfe
Donut Hole Kid

Jay Jablonski
Man in Suit

D.A. Obahor
Moviegoer

Eugenia Kuzmina
Alina

Mary McCloud
Christina

Lilly Singh
Cathy

Harry Beckstead
Valet Theo

Michele Ziegler
Diane

Martha Stewart
Herself

Colin Egglesfield
Astronaut