Woody Harrelson
Dr. Michael Reynolds

Jon Seda
Brandon 'Blue' Monroe

Anne Bancroft
Dr. Renata Baumbauer

Alexandra Tydings
Victoria Reynolds

Matt Mulhern
Dr. Chip Byrnes

Talisa Soto
Navajo Woman

Lawrence Pressman
Agent in Charge Collier

Michael O'Neill
Agent Moreland

Harry Carey, Jr.
Cashier

Carmen Dell'Orefice
Arabella Reynolds

Brooke Ashley
Calantha Reynolds

Andrea Roth
Head Nurse

Bob Minor
Deputy Lynch

Sal Landi
Deputy #2

Kelly Perine
Fellow in Oncology

Andy Berman
Fellow in Oncology

Kirsten Getchell
Sally Byrnes

John Christian Graas
Young Michael Reynolds

Christopher Masterson
Jimmy Reynolds

Antwon Tanner
Smokes

Tony Epper
Hay Hauler

Mickey Jones
Fuzzy, Biker #1

Gregory Scott Cummins
Biker #2

Elaine Kagan
Woman at Gas Station

Brett Harrelson
Younger Highway Patrol Officer

Zoe Trilling
Mini-Mart Cashier

Betty Carvalho
Rosa

Robert Downey Sr.
Telephone Voices