Sidney Toler
Charlie Chan

Victor Sen Yung
Jimmy Chan

Leo G. Carroll
Professor Gordon

Lionel Atwill
Dr. Suderman

Robert Lowery
Dick Kenyon

Marjorie Weaver
Paula Drake

Cora Witherspoon
Susie Watson

Don Beddoe
Frederick Ross

Leonard Mudie
Gerald Pendleton

Charles Middleton
Jeremiah Walters

Claire Du Brey
Sarah Walters

James Burke
Wilkie, house detective

Richard Keene
Buttons, ship's steward

Harry Strang
Seaman Guarding Pendleton

Harlan Briggs
San Francisco Coroner

Layne Tom Jr.
Willie Chan

C. Montague Shaw
Inspector Duff

Cliff Clark
Lieutenant Wilson

Kay Linaker
Linda Pendleton

Paul McVey
Mrs. Pendleton's Doctor

Wade Boteler
Honolulu Police Chief

Emmett Vogan
Hotel Manager

John Dilson
Police Doctor at Hotel

J. Anthony Hughes
Detective Wilson, Chan's agent

Walter Miller
Ship's Officer (uncredited)

Al Kikume
Cop Extra in Chan's Office