Stephanie Sigman
Sister Charlotte

Talitha Eliana Bateman
Janice

Lulu Wilson
Linda

Anthony LaPaglia
Samuel Mullins

Miranda Otto
Esther Mullins

Grace Caroline Currey
Carol

Philippa Coulthard
Nancy

Samara Lee
Annabelle "Bee" Mullins

Tayler Buck
Kate

Lou Lou Safran
Tierney

Brad Greenquist
Victor Palmeri

Mark Bramhall
Father Massey

Joseph Bishara
Annabelle Demon

Alicia Vela-Bailey
Evil Mullins / Demon Hands

Adam Bartley
Officer Form

Lotta Losten
Adoption agent

Brian Howe
Mr. Higgins

Kerry O'Malley
Mrs. Higgins

Annabelle Wallis
Mia Form

Ward Horton
John Form

Fred Tatasciore
Demon (voice)

Bonnie Aarons
Demon Nun (uncredited)

Liam James Ramos
Small Boy (uncredited)

Emily Brobst
Demon Nun (uncredited)