David Arquette
Dewey Riley

Neve Campbell
Sidney Prescott

Courteney Cox
Gale Weathers

Matthew Lillard
Stu Macher

Rose McGowan
Tatum Riley

Skeet Ulrich
Billy Loomis

Jamie Kennedy
Randy Meeks

W. Earl Brown
Kenny Brown

Joseph Whipp
Sheriff Burke

Liev Schreiber
Cotton Weary

Drew Barrymore
Casey Becker

Roger L. Jackson
Ghostface (voice)

Kevin Patrick Walls
Steven Orth

Lawrence Hecht
Neil Prescott

C.W. Morgan
Hank Loomis

Frances Lee McCain
Mrs. Riley

Ryan Kennedy
Expelled Teen #2

Leonora Scelfo
Cheerleader in Bathroom

Nancy Anne Ridder
Girl in Bathroom

Lisa Canning
Reporter with Mask

Henry Winkler
Principal Arthur Himbry (uncredited)

Linda Blair
Obnoxious Reporter (uncredited)

Wes Craven
Fred the Janitor (uncredited)

Lynn McRee
Maureen Prescott (uncredited)