Jean Harlow
Lola Burns

Lee Tracy
E.J. 'Space' Hanlon

Frank Morgan
Pops Burns

Franchot Tone
Gifford Middleton

Pat O’Brien
Jim Brogan

Una Merkel
Mac

Ted Healy
Junior Burns

Ivan Lebedeff
Marquis Hugo di Binelli di Pisa

Isabel Jewell
Nellie, Junior's Girlfriend

Louise Beavers
Loretta

Leonard Carey
Winters

Mary Forbes
Mrs. Middleton

C. Aubrey Smith
Mr. Middleton

June Brewster
Alice Cole

Minerva Urecal
Autograph Seeker (uncredited)

Dorothy DeBorba
Girl Getting Lola's Autograph at Table (uncredited)

Grace Hayle
Mrs. Titcomb (uncredited)

Martha Sleeper
Lola's Hair Stylist (uncredited)

Hooper Atchley
Car Salesman (uncredited)

Ed Brady
Photographer (uncredited)

Don Brodie
Photographer (uncredited)

James Burke
First Immigration Officer (uncredited)

Primo Carnera
Primo Carnera - in the Opening Montage (uncredited)

Billy Dooley
Man Claiming to Be Lola's Husband (uncredited)

Edward Gargan
Second Immigration Officer (uncredited)

Ethel Griffies
Mrs. Ward - Orphanage Representative (uncredited)

Tenen Holtz
White - Lola's Agent (uncredited)

Kenner G. Kemp
Nightclub Patron (uncredited)

Donald Kerr
Monte - Lola's Makeup Man (uncredited)

Wilbur Mack
Van Randolph - Hugo's Lawyer (uncredited)

Philo McCullough
Reporter (uncredited)

Greta Meyer
Lola's Masseuse (uncredited)

Miki Morita
Yokahama (uncredited)

Louis Natheaux
Car Salesman (uncredited)

William Newell
Lola's Chauffeur (uncredited)

Dennis O'Keefe
Nightclub Patron (uncredited)

Shirley Ross
Singer (uncredited)

Dale Van Sickel
Cocoanut Grove Patron (uncredited)

Morgan Wallace
H.E. Gillette (uncredited)

Kathrin Clare Ward
Older Orphanage Nurse (uncredited)

Ruth Warren
Miss Carroll from Photoplay Magazine (uncredited)