Simon Amstell
Narrator

Linda Bassett
Dr Yasmine Vondenburg

Martin Freeman
Jeff

Eileen Atkins
Dorothy

Joanna Lumley
Herself (voice)

Lindsay Duncan
Maude

Alex Lawther
Volunteer: Joey

Gemma Jones
Davina

John Macmillan
Troye King Jones

Claire Keelan
Lindsay Graber

James Smith
Graham Watkins

Samantha Spiro
Edith Paper

Martin Sims
Prof. Charles Grandage

Simon Chandler
Barnaby Jones

Michael Fenton Stevens
Peter Smithball

Jumayn Hunter
Robert

Simon Fisher-Becker
Kevin

Collette Cooper
Georgina

Roy Sampson
Leon

George Keywood
Larry

Vanessa Earl
Lisa Thomas

Scott Chambers
Kyle

Will Rastall
Bertie

James Bloor
Vegan

Josephine Butler
Teacher

Matthew Beard
Jeremy (voice)

Karl Theobald
Daddy (voice)

Margaret Clunie
Model

Mawaan Rizwan
Freddy Javashankar

Robert Cawsey
Confused Man

Natalie Jones
Confused Woman

Kirsty Wark
Herself

Lorraine Kelly
Herself

Vanessa Feltz
Herself

Clive Myrie
Himself

Racheal Ofori
Patricia

Jamie Adenuga
Himself