Margot Robbie
Harley Quinn

Rosie Perez
Renee Montoya

Mary Elizabeth Winstead
Helena Bertinelli / Huntress

Jurnee Smollett
Dinah Lance / Black Canary

Ewan McGregor
Roman Sionis

Ella Jay Basco
Cassandra Cain

Chris Messina
Victor Zsasz

Ali Wong
Ellen Yee

David Ury
Sleazy Breeder

Sara Montez
Shallow Friend #1 / Kathrine

Izabel Pakzad
Shallow Friend #2

Daniel Bernhardt
Sionis' Chauffeur

Kc Strubbe
Naïve Teammate

Jacky Shu
Skeptical Teammate

Paloma Esparza Rabinov
Bitchy Teammate

Derek Wilson
Detective Tim Munroe

Joe Bucaro III
Carlos Rossi

François Chau
Mr. Keo

Miyuki Matsunaga
Mrs. Keo

Anna Mikami
Miss Keo (16 yrs)

Bruno Oliver
Bodega Cook (Sal)

Keisha Tucker
Roller Derby Girl

Matthew Willig
Happy

Jeremy Denzlinger
Desk Sergeant

Michael Masini
Officer Drago

Charles Carpenter
Processing Officer

Daniel Cole
Patrol Cop

Jesse Bush
Patrol Cop

Steven Williams
Captain Patrick Erickson

Charlene Amoia
Maria Bertinelli

Paul Lasa
Helena's Father

Ella Mika
Young Helena

Robert Catrini
Stefano Galante

Eddie Alfano
Helena's Bodyguard

Chris Carnel
Desk Sergeant

Buddy Sosthand
Coffee Cup Cop

Tim Sitarz
Donut Cop

Shawn Balentine
Key Card Cop

Shahaub Roudbari
Smarmy Guy

Pramod Kumar
Irate Shopkeeper

K.K. Barrett
Dr. Aguilar

David Bianchi
Sionis Henchman #1

Simon Rhee
Cell Guard

Terrence Julien
Cell Guard

George Crayton
Prisoner

Caleb Spillyards
Prisoner

Qiang Li
Prisoner

Anthony N.
Prisoner

Sala Baker
Prisoner

Bryan Sloyer
Prisoner

Kofi Yiadom
Mercenary

Efka Kvaraciejus
Mercenary

Sam Hargrave
Mercenary

Dennis Keiffer
Mercenary

Dana Lee
Doc

Bojana Novaković
Erika

Andy Hoff
Erika's Date

Eric Michael Cole
Disgruntled Man

Oakley Lehman
Mercedes Gang

Richard King
Mercedes Gang

Tim Rigby
RR Passenger

Judy Kain
Bespectacled Secretary (uncredited)

Rj Wayne
Tough Guy (uncredited)

Zack Whyel
Roman's Healer (uncredited)

Ellay Watson
Roller Derby Fan (uncredited)

Karen Teliha
Nun (uncredited)

Nev Smith
Gotham Detective (uncredited)

Greice Santo
Scantily Clad Crystal (uncredited)

Zeus Sagittarius
Roman's Goon (uncredited)

Talon Reid
Roman's Goon (uncredited)

Matthew Parry-Jones
Club Goer (uncredited)

Brian Nuesi
Husband (uncredited)

Adinett Nsabimana
Girl at the Bar (uncredited)

Brandon Garic Notch
Roman's Lift Goon (uncredited)

Anthony Molinari
Mafiosi (uncredited)

Ego Mikitas
Don (uncredited)

Lenora May
Mrs. Marcucci (uncredited)

Jeff Lipary
BBB Gang Member (uncredited)

Brandon Irvin
Roman's Goon (uncredited)

Damon Hoffman
Bodybuilder (uncredited)

William Guirola
Thug (uncredited)

Nico Greetham
Young Goon (uncredited)

Luis Richard Gomez
Harley Super Fan (uncredited)

Shad Gaspard
Lords Leader (uncredited)

Julian Garcia
Roman's Goon (uncredited)

Eddie J. Fernandez
Gauntlet Cop (uncredited)

Mike Ferguson
Lord of the Avenue (uncredited)

Gerald Downey
Judge (uncredited)

Jack Dourakos
Club Goer (uncredited)

Sadyr Diouf
Roman's Goon (uncredited)

Dan Cole
Officer Timm (uncredited)

Jason Catron
Sprang Bridge Soldier (uncredited)

David Anthony Buglione
Joe Bertinelli (uncredited)