Philip Seymour Hoffman
Caden Cotard

Samantha Morton
Hazel

Jennifer Jason Leigh
Maria

Michelle Williams
Claire Keen

Catherine Keener
Adele Lack

Emily Watson
Tammy

Tom Noonan
Sammy Barnathan

Sadie Goldstein
Olive (4 years old)

Hope Davis
Madeleine Gravis

Dianne Wiest
Ellen Bascomb / Millicent Weems

Kristen Bush
Actress Playing Claire

Alice Drummond
Actress Playing Frances

Amy Wright
Burning House Realtor

Deirdre O'Connell
Ellen's Mother

Elizabeth Marvel
Warehouse Realtor

Charles Techman
Like Clockwork Patient

Tom Greer
Medic

Josh Pais
Ophthalmologist

Lynn Cohen
Caden's Mother

Jerry Adler
Caden's Father

Daisy Tahan
Ariel

Frank Girardeau
Plumber

Peter Friedman
Emergency Room Doctor

Daniel London
Tom

Robert Seay
David

Stephen Adly Guirgis
Davis

Joe Lisi
Maurice

Michael Medeiros
Eric

Christopher Evan Welch
Pastor

William Ryall
Jimmy

Rosemary Murphy
Frances

John Rothman
Dentist

Paul Sparks
Derek

Tim Guinee
Needleman Actor

Robin Weigert
Adult Olive

Michael Higgins
Actor Playing Man with Nose Bleed

Barbara Haas
Warehouse Actress

Alvin Epstein
Man with Nose Bleed

Gerald Emerick
Man in Line

Chris McGinn
Lady at Caden's Mom's

Portia
Therapy Patient Actress

Nicholas Wyman
Soap Actor Doctor

Amy Spanger
Soap Actress Nurse

Erica Fae
German Woman

Mark Lotito
Minister

Frank Wood
Evaluative Services Doctor