Hugh Grant
The Prime Minister

Alan Rickman
Harry

Emma Thompson
Karen

Liam Neeson
Daniel

Martine McCutcheon
Natalie

Colin Firth
Jamie Bennett

Bill Nighy
Billy Mack

Laura Linney
Sarah

Lúcia Moniz
Aurelia

Andrew Lincoln
Mark

Keira Knightley
Juliet

Chiwetel Ejiofor
Peter

Gregor Fisher
Joe

Martin Freeman
John

Joanna Page
Just Judy

Heike Makatsch
Mia

Thomas Brodie-Sangster
Sam

Kris Marshall
Colin Frissell

Rodrigo Santoro
Karl

Abdul Salis
Tony

Rowan Atkinson
Rufus, Jewellery Salesman

Rory MacGregor
Engineer

Sienna Guillory
Jamie's Girlfriend

Billy Bob Thornton
The US President

Lulu Popplewell
Daisy, Karen's Daughter

Olivia Olson
Joanna Anderson

Nina Sosanya
Annie

Jill Raymond
Pat the Housekeeper

Tim Hatwell
Vicar

Lynden David Hall
The Wedding Singer

Jont Whittington
Guitarist

Dan Fredenburgh
Jamie's Bad Brother

Julia Davis
Nancy the Caterer

Shaughan Seymour
Movie Cameraman

Edward Hardwicke
Sam's Grandfather

Caroline John
Sam's Grandmother

Brian Bovell
Radio Watford DJ

Marcus Brigstocke
Mikey, DJ Interviewer

Richard Hawley
Alex, Deputy Prime Minister

Anthony McPartlin
Ant

Declan Donnelly
Dec

Elisabeth Margoni
Eleonore

Peter Marinker
US Expert

Keir Charles
Press Conference Reporter

Meg Wynn Owen
PM's Secretary

Jo Whiley
Radio DJ

Meredith Ostrom
Billy's Video Vixen

Michael Parkinson
Parky

Michael Fitzgerald
Michael, Sarah's Brother

John Sharian
Wisconsin Taxi Driver

Glenn Conroy
Barman

Ivana Miličević
Stacey, American Dreamgirl

January Jones
Jeannie, American Angel

Elisha Cuthbert
Carol-Anne, American Goddess

Wes Butters
Radio 1 Chart Show DJ

Laura Rees
Record Company Executive

Sheila Allen
Jamie's Mum

Margery Mason
Harris Street Old Lady

Joanna Bacon
Natalie's Mum

Adam Godley
Mr Trench

Ruby Turner
Mrs. Jean Anderson

Arturo Venegas
Mr. Anderson

Claudia Schiffer
Carol

Helder Costa
Mr. Barros

Carla Vasconcelos
Sophia Barros

Paul Heasman
Airport Guard

Tony Lucken
Airport Guard

Raul Atalaia
Restaurant Proprietor

Nancy Sorrell
Greta

Shannon Elizabeth
Harriet, the Sexy One

Denise Richards
Carla, the Real Friendly One

Richard Curtis
Trombone Player (uncredited)

Frances de la Tour
Lesbian Lover (uncredited)

Nia Jermin
Head Chorister (uncredited)

Jeanne Moreau
Taxi Passenger at Marseille Airport (uncredited)

Anne Reid
Headmistress (uncredited)