William Powell
Philo Vance

Mary Astor
Hilda Lake

Eugene Pallette
Detective Heath

Ralph Morgan
Raymond Wrede

Robert McWade
District Attorney Markham

Robert Barrat
Archer Coe

Frank Conroy
Brisbane Coe

Etienne Girardot
Dr. Doremus

Paul Cavanagh
Thomas MacDonald

Arthur Hohl
Gamble the Butler

Helen Vinson
Doris Delafield

Jack La Rue
Eduardo Grassi

Wade Boteler
Desk Sergeant Mellish (uncredited)

Don Brodie
Police Photographer (uncredited)

James Burke
Policeman Who Lets Dog Out (uncredited)

George Chandler
Reporter at Police Station (uncredited)

Spencer Charters
Sergeant Snitkin (uncredited)

Virginia Dabney
Girl (uncredited)

Milton Kibbee
Reporter (uncredited)

Harry Morgan
Gamble (uncredited)

Henry O'Neill
Dubois (uncredited)

Paul Panzer
Baggage Clerk (uncredited)

Leo White
Chicago Hotel Clerk (uncredited)

Renee Whitney
Telephone Operator (uncredited)

Charles C. Wilson
Detective Hennessy (uncredited)