Dwayne Johnson
Krypto the Superdog (voice)

Kevin Hart
Ace the Bat-Hound (voice)

John Krasinski
Clark Kent / Superman (voice)

Keanu Reeves
Bruce Wayne / Batman (voice)

Kate McKinnon
Lulu (voice)

Vanessa Bayer
PB (voice)

Natasha Lyonne
Merton (voice)

Diego Luna
Chip (voice)

Jameela Jamil
Diana Prince / Wonder Woman (voice)

Marc Maron
Lex Luthor (voice)

Dascha Polanco
Jessica Cruz / Green Lantern (voice)

Olivia Wilde
Lois Lane (voice)

Jemaine Clement
Arthur Curry / Aquaman (voice)

Daveed Diggs
Victor Stone / Cyborg (voice)

John Early
Barry Allen / The Flash (voice)

Ben Schwartz
Mark / Fire Guinea Pig (voice)

Thomas Middleditch
Keith / Ice Guinea Pig (voice)

Maya Erskine
Mercy Graves (voice)

Yvette Nicole Brown
Patty (voice)

Alfred Molina
Jor-El (voice)

Lena Headey
Lara (voice)

Keith David
Dog-El (voice)

Busy Philipps
Foofy Dog (voice)

Dan Fogler
Carl / Pilot / Racer (voice)

David Pressman
Corgi (voice)

Sam Levine
Waffles / Robot Guards (voice)

Jared Stern
Bathtub Guy / JLA Hotline (voice)

Michelle Morgan
Mech Suit (voice)

Richard Arnold
Waffles (Uk Dub)