Tom Hardy
Eddie Brock / Venom

Woody Harrelson
Cletus Kasady / Carnage

Michelle Williams
Anne Weying

Naomie Harris
Frances Louise Barrison / Shriek

Reid Scott
Dr. Dan Lewis

Stephen Graham
Detective Mulligan

Peggy Lu
Mrs. Chen

Sian Webber
Dr. Pazzo

Michelle Greenidge
Mugging Victim

Rob Bowen
Beaten Mugger

Laurence Spellman
Patient

Little Simz
Little Simz

Jack Bandeira
Young Cletus

Olumide Olorunfemi
Young Shirek

Scroobius Pip
Siegfried

Amrou Al-Kadhi
Host Two

Brian Copeland
Rodeo Beach Reporter

Stewart Alexander
Warden

Sean Delaney
Young Detective Mulligan

Ed Kear
Reveler

Emma Lau
Reveler

Christopher Godwin
Headmaster (1997)

Tiffanie Thomas
San Quentin Tier Guard

Rocky Capella
Valet Car Park

Greg Lockett
San Francisco Police Department Officer

Sonny Ashbourne Serkis
Plunger Man

Otis Winston
Street Man

Reece Shearsmith
Priest

Simon Connolly
Grieving Father

Rachel Handshaw
Grieving Mother

Amanda Foster
Victim's Sister

Akie Kotabe
Victim's Brother

Eric Sigmundsson
Startled Witness

Chabris Napier-Lawrence
Ravenscroft Guard

Larry Olubamiwo
Ravenscroft Guard

Jose Palma
San Quentin Last Meal Guard

Jamal Ajala
Ravenscroft Orderly

James D. Weston II
San Quentin Commander

Rosie Marcel
Detective in Bathroom

J.K. Simmons
J. Jonah Jameson (uncredited)

Tom Holland
Peter Parker / Spider-Man (uncredited)

David Zepeda
Max Irázabal (uncredited)