Anton Yelchin
Charley Brewster

Colin Farrell
Jerry Dandrige

Toni Collette
Jane Brewster

David Tennant
Peter Vincent

Imogen Poots
Amy Petersen

Christopher Mintz-Plasse
Ed Thompson

Dave Franco
Mark

Reid Ewing
Ben Wegner

Will Denton
Adam

Emily Montague
Doris

Chris Sarandon
Jay Dee

Gracie Gillam
Bee

Lisa Loeb
Victoria

Brian Huskey
Rick

Mike Miller
Store Guy

Marya Beauvais
Mrs. Granada

Kent Kirkpatrick
Teacher

Arron Shiver
Cop #1

Rick A. Ortega Jr.
Cop #2

Charlie B. Brown
Doctor

Rebekah Wiggins
Passing Nurse

Eb Lottimer
Adam's Dad

Liezl Carstens
Show Nymph #1

Laura Aidan
Show Nymph #2

Alma Sisneros
Show Nymph #3

Chris Ranney
Guard

Lovie Johnson
D.J.

Jerry G. Angelo
Guy on Dance Floor

Tait Fletcher
Nightclub Security Guy

Bonnie Morgan
Vamp #1

Michelle Waterson-Gomez
Vamp #2

Dee Bradley Baker
Jerry's Vampire Vocals (voice)