Flula Borg
Officer Doug (voice)

Alex Cazares
Staci (voice)

Rhys Darby
Happy Sedengry (voice)

Pierce Gagnon
Timothy Templeton (voice)

Jake Green
Bootsy Calico (voice)

JP Karliak
Boss Baby (voice)

Hope Levy
Mom / Peg (voice)

Wendie Malick
Wendi (voice)

Victor Raider-Wexler
Frederic Estes (voice)

Kevin Michael Richardson
Jimbo (voice)

Sarah-Nicole Robles
Marisol (voice)

Brandon Scott
Hendershot (voice)

Eric Bell Jr.
Triplets (voice)

Cynthia Erivo
Turtleneck Superstar (voice)

Jeff Bennett
Puzzle Computers (voice)

Diedrich Bader
Junior Fancy (voice)

Kari Wahlgren
R&D Baby Simmons (voice)