Millie Bobby Brown
Michelle

Chris Pratt
Keats

Ke Huy Quan
Dr. Amherst / P.C (voice)

Jason Alexander
Ted / Wingman

Woody Norman
Christopher

Giancarlo Esposito
Colonel Bradbury / The Marshall

Stanley Tucci
Ethan Skate

Woody Harrelson
Mr. Peanut (voice)

Anthony Mackie
Herman (voice)

Brian Cox
Popfly (voice)

Jenny Slate
Penny Pal (voice)

Hank Azaria
Perplexo (voice)

Colman Domingo
Wolfe (voice)

Alan Tudyk
Cosmo (voice)

Ann Russo
Mom

Greg Cromer
Dad

Vince Pisani
Science Professor

Camrus Johnson
Corporal Carson

Kurt Loder
Kurt Loder

Holly Hunter
Madeline Vance

Will Lyman
Documentary Narrator (voice)

Tuc Watkins
Arthur Meadows

Billy Gardell
Garbage Bot (voice)

Merle Dandridge
News Anchor

Necar Zadegan
Farah Bedi

Lia Mariella Russo
Cheerleader

Marin Hinkle
Ms. Sablinsky

Antoinette LaVecchia
Elena Skate

Rahul Kohli
Miles Watlow

Michael Trucco
Ben Alcott

Joe Russo
Skeevy Bot (voice)

Rob Gronkowski
Blitz (voice)

Susan Leslie
Mrs. Scissors (voice)

Patrick Newall
Bumper Car Drone Pilot

Terence Lee
Cosmo Capture Drone

Alan Boell
Sentre Tech #1

Myles Alexander Evans
Sentre Tech #2

Patti Harrison
Ligotti

Chris Castaldi
Determined Drone Pilot

Terry Notary
Mr. Peanut / Pop Fly / Sentre Drones / Ice Cream Bot / Skeeve Bot

Adam Croasdell
The Marshall / Taco Bot / Sentry Bot / Blitz

Devyn Dalton
Cosmo

Gabrielle Maiden
Penny Pal / Mrs. Scissors / Happy Pill Bot / Sentre Drones

Martin Klebba
Herman / Milkman Bot

Katelin Chesna
Hospital Doctor (uncredited)

Sebastian Soler
Orderly (uncredited)

Bill Clinton
Himself (archive footage) (uncredited)

Nancy Pelosi
Herself (archive footage) (uncredited)