Benicio del Toro
Lawrence Talbot

Anthony Hopkins
Sir John Talbot

Emily Blunt
Gwen Conliffe

Hugo Weaving
Inspector Francis Abberline

Geraldine Chaplin
Maleva

Art Malik
Singh

Antony Sher
Dr. Hoenneger

David Schofield
Constable Nye

Cristina Contes
Solana Talbot

David Sterne
Kirk

Elizabeth Croft
Ophelia (uncredited)

Simon Merrells
Ben Talbot

Asa Butterfield
Young Ben

Olga Fedori
Young Gypsy Woman

Lorraine Hilton
Mrs. Kirk

John Owens
Asylum Doctor #1

Gemma Whelan
Gwen's Maid

Nicholas Day
Colonel Montford

Clive Russell
MacQueen

Michael Cronin
Dr. Lloyd

Max von Sydow
Passenger on Train (Director's Cut) (uncredited)

Roger Frost
Reverend Fisk

Oliver Adams
Gypsy Boy

Emil Hostina
Gypsy Man / Bear Handler

Rick Baker
Gypsy Man / First Killed

Jessica Manley
Gypsy Mother

Jordan Coulson
Wolf Boy

Ian Peck
Creepy Guard

David Keyes
Custodian

C.C. Smiff
Police Officer #3

Anthony Debaeck
Gypsy Driver

Waseem Abbas
Gypsy Boy (uncredited)

Julie Eagleton
Woman in Theatre (uncredited)

Kate Dion-Richard
The Screaming Girl (uncredited)

Salo Gardner
Villager (uncredited)

Andy Gathergood
Villager 1 (uncredited)

Richard Hansell
Asylum Doctor (uncredited)

Sam Hazeldine
Horatio (uncredited)

Mia McKenna-Bruce
Street Urchin (uncredited)

Brigitte Millar
Gertrude (uncredited)

Claude Starling
Asylum Doctor #4 (uncredited)

Karim Theilgaard
Gypsy Man 3 (uncredited)

Christian Wolf-La'Moy
Gentleman in Top Hat (uncredited)

Branko Tomović
Roman (uncredited)