Shia LaBeouf
Sam Witwicky

Megan Fox
Mikaela Banes

Peter Cullen
Optimus Prime (voice)

Hugo Weaving
Megatron (voice)

Tony Todd
Fallen (voice)

Josh Duhamel
Major Lennox

Tyrese Gibson
USAF Chief Master Sergeant Epps

John Turturro
Simmons

Ramón Rodríguez
Leo Spitz

Kevin Dunn
Ron Witwicky

Julie White
Judy Witwicky

Isabel Lucas
Alice

John Benjamin Hickey
Galloway

Matthew Marsden
Special Air Service Forces

Andrew Howard
Special Air Service Forces

Michael Papajohn
Cal

Glenn Morshower
General Morshower

John Eric Bentley
Aide

Erin Naas
Arcee Rider

Rainn Wilson
Professor Colan

Katie Lowes
April the Resident Assistant

Jonathon Trent
Fassbinder

Walker Howard
Sharsky

America Olivo
Frisbee Girl

Aaron Hill
Frat Guy

Jareb Dauplaise
Frat Guy

John Sanderford
Pundit

Christopher Curry
Pundit

Cas Anvar
Egyptian Interpol Officer

Michael Benyaer
Egyptian Interpol Officer

Deep Roy
Egyptian Guard

Spencer Garrett
Air Force Chief of Staff

Aaron Norvell
Air Force Military Police

Eric Pierpoint
NSA Officer

Annie Korzen
Simmons Mom

Sean T. Krishnan
Yakov

David Bowe
Smithsonian Guard

Kamal Jones
Smithsonian Guard

Aaron Lustig
Reporter

Jim Holmes
Reporter

Cornell Womack
FBI Director

Derek Alvarado
Joint Ops Staff

Alex Fernandez
Joint Ops Staff

Casey Nelson
Joint Ops Staff

John Nielsen
USS Roosevelt Captain

Rick Cramer
Diego Garcia Soldier

Arnold Chun
Diego Garcia Soldier

Marc Evan Jackson
Commander, US Central Command

Josh Kelly
Strike Force Team

Joel Lambert
Strike Force Team

Geoff Reeves
Strike Force Team

Brian Shehan
Strike Force Team

Mark Ryan
Jetfire (voice)

Reno Wilson
Mudflap (voice)

Jess Harnell
Ironhide (voice)

Robert Foxworth
Ratchet (voice)

André Sogliuzzo
Sideswipe (voice)

Grey DeLisle
Arcee (voice)

Charlie Adler
Starscream (voice)

Frank Welker
Soundwave / Devastator / Reedman (voice)

Tom Kenny
Wheelie / Skids (voice)

John Di Crosta
Doctor (voice)

Michael York
Prime #1 (voice)

Kevin Michael Richardson
Prime #2 / Skipjack (voice)

Robin Atkin Downes
Prime #3 (voice)

Jenn An
Astronomy Student (uncredited)

Alexandra Begg
College Student (uncredited)

Caitlin Dulany
CNN Reporter (uncredited)

Andrew Hwang
Mandarin Blogger (uncredited)

Matt Iseman
C-17 Pilot (uncredited)

Shayna Ryan
French Cafe Patron (uncredited)

Karina Michel
Reporter (uncredited)

Chester the Chihuahua
Mojo (uncredited)