Warren Beatty
Dick Tracy

Al Pacino
Big Boy Caprice

Madonna
Breathless Mahoney

Dustin Hoffman
Mumbles

James Caan
Spaldoni

Charlie Korsmo
Kid

Glenne Headly
Tess Trueheart

Mandy Patinkin
88 Keys

Seymour Cassel
Sam Catchem

James Keane
Pat Patton

Charles Durning
Chief Brandon

William Forsythe
Flattop

James Tolkan
Numbers

Ed O'Ross
Itchy

Dick Van Dyke
D.A. Fletcher

R.G. Armstrong
Pruneface

Michael J. Pollard
Bug Bailey

Paul Sorvino
Lips Manlis

Henry Silva
Influence

Tom Signorelli
Mike

Stig Eldred
Shoulders

Jim Wilkey
Stooge

Neil Summers
The Rodent

Chuck Hicks
The Brow

Lawrence Steven Meyers
Little Face

Tony Epper
Steve the Tramp

Estelle Parsons
Mrs. Trueheart

Allen Garfield
Reporter

John Schuck
Reporter

Charles Fleischer
Reporter

Mary Woronov
Welfare Person

Kathy Bates
Mrs. Green

Ian Wolfe
Forger

Henry Jones
Night Clerk

Catherine O'Hara
Texie Garcia

Robert Beecher
Ribs Mocca

Lew Horn
Lefty Moriarty

Michael Donovan O'Donnell
McGillicuddy

Robert Costanzo
Lips' Bodyguard

Jack Kehoe
Customer at Raid

Marshall Bell
Lips' Cop

Mike Hagerty
Doorman

Arthur Malet
Diner Patron

Hamilton Camp
Store Clerk

Ed McCready
Cop at Tess'

Colm Meaney
Cop at Tess'

Bert Remsen
Bartender

Frank Campanella
Judge Harper

Bing Russell
Club Ritz Patron

Tom Finnegan
Uniform Cop at Ritz

John Moschitta Jr.
Radio Announcer (voice)

Neil Ross
Radio Announcer (voice)

Walker Edmiston
Radio Announcer (voice)

Mike Mazurki
Old Man at Hotel

Rita Maye Bland
Dancer

Karen Russell
Dancer

Michelle Johnston
Dancer

Tamara Carrera
Cigarette Girl (uncredited)

Sheila Lussier
Gangster's Girlfriend (uncredited)

Bruce Mahler
Reporter (uncredited)