Dennis Quaid
Charlie Wessler (segment "The Pitch")

Greg Kinnear
Griffin Schraeder (segment "The Pitch")

Hugh Jackman
Davis (segment "The Catch")

Kate Winslet
Beth (segment "The Catch")

Jeremy Allen White
Kevin (segment "Homeschooled")

Liev Schreiber
Robert (segment "Homeschooled")

Naomi Watts
Samantha (segment "Homeschooled")

Anna Faris
Vanessa (segment "The Proposition")

Chris Pratt
Jason (segment "The Proposition")

Kieran Culkin
Neil (segment "Veronica")

Emma Stone
Veronica (segment "Veronica")

Richard Gere
Robert (segment "iBabe")

Kate Bosworth
Arlene (segment "iBabe")

Justin Long
Fake Robin (segment "Super Hero Speed Dating")

Jason Sudeikis
Fake Batman (segment "Super Hero Speed Dating")

Uma Thurman
Fake Lois Lane (segment "Super Hero Speed Dating")

Bobby Cannavale
Fake Superman (segment "Super Hero Speed Dating")

Kristen Bell
Fake Supergirl (segment "Super Hero Speed Dating")

John Hodgman
Fake Penguin (segment "Super Hero Speed Dating")

Leslie Bibb
Fake Wonder Woman (segment "Super Hero Speed Dating")

Will Carlough
Fake Riddler (segment "Super Hero Speed Dating")

Katrina Bowden
Woman (segment "Super Hero Speed Dating")

Phil Crowley
Narrator (segment "Machine Kids") (voice)

Christopher Mintz-Plasse
Mikey (segment "Middleschool Date")

Chloë Grace Moretz
Amanda (segment "Middleschool Date")

Patrick Warburton
Dad (segment "Middleschool Date")

Jimmy Bennett
Nathan (segment "Middleschool Date")

Matt Walsh
Amanda's Dad (segment "Middleschool Date")

Gerard Butler
Leprechaun 1 & 2 (segment "Happy Birthday")

Johnny Knoxville
Pete (segment "Happy Birthday")

Seann William Scott
Pete (segment "Happy Birthday")

Halle Berry
Emily (segment "Truth or Dare")

Stephen Merchant
Donald (segment "Truth or Dare")

Terrence Howard
Coach Jackson (segment "Victory's Glory")

Elizabeth Banks
Amy (segment "Beezel")

Josh Duhamel
Anson (segment "Beezel")

Common
Bob Mone (segment "The Pitch")

Charlie Saxton
Jay (segment "The Pitch")

Will Sasso
Jerry (segment "The Pitch")

Odessa Rae
Danita (segment "The Pitch")

Seth MacFarlane
Seth MacFarlane (segment “The Pitch”)

Mike Meldman
Mike Meldman (segment "The Pitch")

Julie Claire
Pamela (segment "The Catch")

Katie Finneran
Angie (segment "The Catch")

Roy Jenkins
Ray (segment "The Catch")

Rocky Russo
Jake, the Waiter (segment "The Catch")

Alex Cranmer
Sean (segment "Homeschooled")

Julie Ann Emery
Clare (segment "Homeschooled")

Austin Cope
High School Student (segment "Homeschooled")

JB Smoove
Larry (segment "The Proposition")

Jarrad Paul
Bill (segment "The Proposition")

Maria Arcé
Christine (segment "The Proposition")

Aaron LaPlante
Friend (segment "The Proposition")

Arthur French
Old Man (segment "Veronica")

Cherina Monteniques Scott
iBabe #2 (segment "iBabe")

Jack McBrayer
Brian (segment "iBabe")

Aasif Mandvi
Robert (segment "iBabe")

Marc Ambrose
"Chappy" (segment "iBabe")

Julie McNiven
ATM Woman (segment "Machine Kids")

Rightor Doyle
Photocopier Man 1 (segment "Machine Kids")

Esti Ginzburg
Fairy (segment "Happy Birthday")

Sayed Badreya
Large Man (segment "Truth or Dare")

Snooki
Snooki (segment "Truth or Dare")

Ricki Lander
Nurse Elizabeth (segment "Truth or Dare")

Paloma Felisberto Bilson
Bachelorette Party Girl (segment "Truth or Dare")

Jasper Grey
Patron (segment "Truth or Dare")

Zen Gesner
Stripper (segment "Truth or Dare")

Aaron Jennings
Anthony (segment "Victory's Glory")

Jay Ellis
Lucious (segment "Victory's Glory")

Brett Davern
White Guy 2 (segment "Victory's Glory")

Evan Dumouchel
White Guy 3 (segment "Victory's Glory")

Sean A. Rosales
White Guy 4 (segment "Victory's Glory")

Mandy Kowalski
Cheerleader (segment "Victory's Glory")

Eric Stuart
Narrator (segment "Victory's Glory")

Emily Alyn Lind
Birthday Girl (segment "Beezel")

Michelle Gunn
Mommy (segment "Beezel")