Jim Carrey
Grinch

Taylor Momsen
Cindy Lou Who

Jeffrey Tambor
Mayor Augustus Maywho

Christine Baranski
Martha May Whovier

Bill Irwin
Lou Lou Who

Molly Shannon
Betty Lou Who

Clint Howard
Whobris

Josh Ryan Evans
8-Year-Old Grinch

Mindy Sterling
Clarnella

Bryce Dallas Howard
Surprised Who

Lacey Kohl
Christina Whoterberry

Rachel Winfree
Rose

Rance Howard
Elderly Timekeeper

Jeremy Howard
Drew Lou Who

T.J. Thyne
Stu Lou Who

Nadja Pionilla
Junie

Jim Meskimen
Officer Wholihan

David Costabile
Biker Who

Mary Stein
Miss Rue Who

James Ritz
Crazy Mose

Deep Roy
Post Office Clerk

Jessica Sara
Sophie

Mason Lucero
Who Boy

Ben Bookbinder
8-Year-Old Augustus Maywho

Michaela Gallo
Who Schoolgirl

Landry Allbright
8-Year-Old Martha May Whovier

Reid Kirchenbauer
8-Year-Old Whobris

Rebecca Chace
Shopper

Suzanne Krull
Shopper

Steve Kehela
Shopper

Lillias White
Shopper

Rain Pryor
Shopper

John Alexander
Shopper

Kevin Isola
Tree Trimmer

Gavin Grazer
Yodeler

Walter Franks
Clerk

Verne Troyer
Band Member

Q'orianka Kilcher
Little Choir Member

Caroline Williams
Tiny Who Woman

Rick Baker
Puppeteer

Mark Setrakian
Puppeteer

Tim Blaney
Puppeteer

Charles Croughwell
Balloon Who

Frank Welker
Max the Dog (voice)

Anthony Hopkins
Narrator (voice)