Mckenna Grace
Skye (voice)

Taraji P. Henson
Victoria Vance (voice)

Marsai Martin
Liberty (voice)

Iain Armitage
Chase (voice)

Ron Pardo
Mayor Humdinger / Cap'n Turbot (voice)

Lil Rel Howery
Sam Stinger (voice)

Kim Kardashian
Delores (voice)

Chris Rock
Kitty (voice)

Serena Williams
Yoga Yvette (voice)

Alan Kim
Nano (voice)

North West
Mini (voice)

Saint West
Meteor Max (voice)

James Marsden
Hank (voice)

Kristen Bell
Janet (voice)

Will Brisbin
Ryder (voice)

Christian Corrao
Marshall (voice)

Luxton Handspiker
Rubble (voice)

Nylan Parthipan
Zuma (voice)

Callum Shoniker
Rocky (voice)

Dan Duran
Radio Announcer (voice)

Kim Roberts
Mayor Goodway (voice)

Sugith Varughese
Jail Guard (voice)

Joshua Graham
Computer voice (voice)

Neil Crone
Tony (voice)