Sarah Polley
Ana

Ving Rhames
Kenneth

Jake Weber
Michael

Mekhi Phifer
Andre

Ty Burrell
Steve

Michael Kelly
C.J.

Kevin Zegers
Terry

Lindy Booth
Nicole

Jayne Eastwood
Norma

Boyd Banks
Tucker

Inna Korobkina
Luda

Kim Poirier
Monica

Matt Frewer
Frank

Louis Ferreira
Luis

Hannah Lochner
Vivian

Bruce Bohne
Andy

Sanjay Talwar
Doctor Rosen

Kim Roberts
Cora

Tim Post
Reviving Doctor

Matt Sadowski-Austin
EMS Technician

Philip DeWilde
EMS Technician

Phillip MacKenzie
Thrashing Zombie

Mike Realba
Maintenance Man

Laura de Carteret
Washington Politician

Georgia Craig
Anchorwoman

Tino Monte
Istanbul Reporter

Chris Gillett
Older Anchorwoman

Dan Duran
Confused Reporter

Natalie Brown
CDC Reporter

Liz West
CDC Reporter

Scott H. Reiniger
The General

Tom Savini
The County Sheriff

Ken Foree
The Televangelist

Darren Marsman
Maintenance Man Zombie (uncredited)

Zack Snyder
Commando at White House (uncredited)