Nicolas Cage
Edward Malus

Ellen Burstyn
Sister Summersisle

Kate Beahan
Sister Willow

Frances Conroy
Dr. Moss

Molly Parker
Sister Rose / Sister Thorn

Leelee Sobieski
Sister Honey

Diane Delano
Sister Beech

Michael Wiseman
Officer Pete

Erika-Shaye Gair
Rowan Woodward

Christa Campbell
Truck Stop Waitress

Emily Holmes
Station Wagon Mom

Matthew Walker
Sea Plane Pilot

Mary Black
Sister Oak

Christine Willes
Sister Violet

Xantha Radley
Village Sister #1

Tania Saulnier
Attendant #1

Anna Van Hooft
Attendant #2

Kendall Cross
Female Cop

Simon Longmore
Village Male #1

Jacqueline Robbins
Blind Twin #1

Joyce Robbins
Blind Twin #2

Aaron Eckhart
Truck Stop Patron

James Franco
Bar Guy #1

Jason Ritter
Bar Guy #2

Monique Ganderton
Rams Horn Woman (uncredited)