Max Minghella
Jerome

Sophia Myles
Audrey

John Malkovich
Professor Sandiford

Jim Broadbent
Jimmy

Matt Keeslar
Jonah

Ethan Suplee
Vince

Joel David Moore
Bardo

Nick Swardson
Matthew

Anjelica Huston
Art History Teacher

Adam Scott
Marvin Bushmiller

Jack Ong
Professor Okamura

Scoot McNairy
Army-Jacket

Brian Turk
Cliffy

Jeanette Brox
Shilo

Finneus Egan
Vegan

Shelly Cole
Filthy-Haired Girl

Jean St. James
Mom

Cristen Coppen
Preppy Girl

Michael Shamus Wiles
Donald Baumgarten

Katherine Moennig
Candace

Ezra Buzzington
Leslie

Lauren Lee Smith
Beat Girl

Travis Walck
Richard Natwick

Paul Collins
Professor David Zipkin

Marshall Bell
Lonny

Chris L. McKenna
Mikey

Marc Vann
Kevin

Roxanne Day
Jonah's Wife - Marie

Roxanne Hart
Mom Platz

Osman Soykut
Dad Platz

Katija Pevec
Cynthia Platz

Michael Lerner
Art Dealer

Jeff LeBeau
Lawyer

Richard Bakalyan
Cranky Guard

Kimi Reichenberg
Suburban Girl

John Bliss
Vince's Grandpa

Charlie Talbert
Vince's Editor

Alexandra Ryan
Nympho Slut

Bob Golub
Hector

Lauren Bowles
Woman Strangled

Brian Geraghty
Stoob

Valyn Hall
Cute Girl

Curtis Taylor
Coach

Jesse Flanagan
Hurst

Dawn-Lyen Gardner
Coed

Laura Roth
Coed

Alexi Wasser
Female Student

Stacey Travis
Teacher

Wendy Haines
Grenadine Woman

Erik Walker
Punching Bully

Choice Skinner
Cop

Bob Jennings
Cop

Sam Sabbah
Scary Local

Steve Buscemi
Broadway Bob D'Annunzio