Will Ferrell
Ted (Man with the Yellow Hat) (voice)

Drew Barrymore
Maggie (voice)

David Cross
Junior (voice)

Eugene Levy
Clovis (voice)

Joan Plowright
Ms. Plushbottom (voice)

Dick Van Dyke
Mr. Bloomsberry (voice)

Frank Welker
George (voice)

Ed O'Ross
Ivan (voice)

Michael Sorich
"Seen It" Cab Driver (voice)

Billy West
Manager (voice)

Jeff Bennett
Salesman (voice)

Kath Soucie
Animal Control Receptionist (voice)

Clint Howard
Balloon Man (voice)

Shane Baumel
Kid (voice)

Jessie Flower
Kid (voice)

Alexander Gould
Kid (voice)

Terrence Hardy Jr.
Kid (voice)

Hailey Noelle Johnson
Kid (voice)

Kelsey Lansdowne
Kid (voice)

Ariel Winter
Kid (voice)

Kimberly Brooks
Additional Voices (voice)

Wendy Cutler
Additional Voices (voice)

Richard Epcar
Additional Voices (voice)

Treva Etienne
Additional Voices (voice)

Eddie Frierson
Additional Voices (voice)

Donald Fullilove
Additional Voices (voice)

Philip Maurice Hayes
Additional Voices (voice)

Bridget Hoffman
Additional Voices (voice)

Rif Hutton
Additional Voices (voice)

Steve Kehela
Additional Voices (voice)

Donna Lynn Leavy
Additional Voices (voice)

John Mariano
Additional Voices (voice)

Caitlin McKenna
Additional Voices (voice)

Juan Pope
Additional Voices (voice)

Jonny Solomon
Additional Voices (voice)

Mandy Fabian
Additional Voices (voice)

Fred Tatasciore
Additional Voices (voice)