Rainn Wilson
Robert 'Fish' Fishman

Teddy Geiger
Curtis

Josh Gad
Matt Gadman

Emma Stone
Amelia

Christina Applegate
Kim

Jeff Garlin
Stan

Jane Lynch
Lisa

Jason Sudeikis
David Marshall

Will Arnett
Lex

Howard Hesseman
Gator

Fred Armisen
Kerr

Bradley Cooper
Trash

Lonny Ross
Sticks

Jon Glaser
Billy

Jane Krakowski
Carol

Samantha Weinstein
Violet

Demetri Martin
Kip

Aziz Ansari
Aziz

Ellie Knaus
Erica

Laura de Carteret
Amelia's Mom

Steve Adams
Amelia's Dad

Keir Gilchrist
Moby Type Kid

Brittany Allen
I Heart Matt Girl

Vik Sahay
Gary

Mark Forward
Leon

Jonathan Malen
Jeremy

Rebecca Northan
Jeremy's Mother

Simon Sinn
Mr. Lee

Ennis Esmer
Barney

SuChin Pak
Self

Николь Арбур
Trashy Groupie

Jon Cor
Paul

Talia Russo
Amy

Tanya Bevan
Prom Queen Jennifer

Wesley Morgan
Prom King Josh

Pete Best
Self

Jordan Lawson
Crazy Fan (uncredited)