Chevy Chase
Clark Griswold

Beverly D'Angelo
Ellen Griswold

Randy Quaid
Cousin Eddie

Ethan Embry
Rusty Griswold

Marisol Nichols
Audrey Griswold

Miriam Flynn
Cousin Catherine

Shae D'Lyn
Cousin Vicki

Wayne Newton
Wayne Newton

Siegfried Fischbacher
Siegfried

Roy Horn
Roy

Wallace Shawn
Marty

Sid Caesar
Mr. Ellis

Julio Oscar Mechoso
Limo Driver

Julia Sweeney
Mirage Reception Person

Corinna Harney
Girl at Blackjack Table

Christie Brinkley
Woman in Ferrari

Juliette Brewer
Cousin Ruby Sue

John Finnegan
Hoover Dam Guide

Howard Platt
Maitre'd

Maria Cina
Mirage Cashier

C.C. Costigan
Kelli

Shannah Laumeister Stern
Mariah

Bud Ekins
O'Shea's Security Guard

Jerry Weintraub
Jilly

S.A. Griffin
Pit Boss

Lou DiMaggio
Casino Host

Jason Stuart
Buffet Guy

Clinton Brandhagen
Valet

Rusty Meyers
Club Manager

Billy Morrissette
Paramedic #1

Larry Hankin
Preacher

Alana Austin
Tourist (uncredited)

Vanessa Bednar
Hot Pool Model (uncredited)

Jeffrey Donovan
Hotel Employee (uncredited)

Billie Perkins
Casino Guest (uncredited)

Toby Huss
Fake ID Salesman (uncredited)