Tom Hanks
Robert Langdon

Ewan McGregor
Camerlengo Patrick McKenna

Ayelet Zurer
Vittoria Vetra

Stellan Skarsgård
Commander Richter

Pierfrancesco Favino
Inspector Olivetti

Nikolaj Lie Kaas
Assassin

Armin Mueller-Stahl
Cardinal Strauss

Thure Lindhardt
Chartrand

David Pasquesi
Claudio Vincenzi

Cosimo Fusco
Father Simeon

Victor Alfieri
Lieutenant Valenti

Curt Lowens
Cardinal Ebner

Bob Yerkes
Cardinal Guidera

Marc Fiorini
Cardinal Baggia

Carmen Argenziano
Father Silvano Bentivoglio

Howard Mungo
Cardinal Yoruba

Rance Howard
Cardinal Beck

Steve Franken
Cardinal Colbert

Gino Conforti
Cardinal Pugini

Ilya Baskin
Cardinal Petrov

Thomas Morris
Urs Weber

Jonas Fisch
Adrian Bachman

August Wittgenstein
Swiss Guardsman

Ben Bela Böhm
Swiss Guardsman

Jeffrey Boehm
Swiss Guard Blue

Steve Kehela
American Reporter

Ursula Brooks
BBC Reporter

Rashmi
British Reporter

Yan Cui
Chinese Reporter

Fritz Michel
French Reporter

Maria Cristina Heller
Italian Reporter

Rafael Petardi
Italian Reporter

Yesenia Adame
Mexican Reporter

Kristof Konrad
Polish Reporter

Masasa Moyo
South African Reporter

Ed Francis Martin
South American Reporter

Cheryl Howard
CERN Scientist

Endre Hules
CERN Scientist

Norbert Weisser
CERN Scientist

Raffi Di Blasio
Protester

Todd Schneider
Carabinieri

Rocco Passafaro
Carabinieri

Emanuele Secci
Carabinieri

Anna Katarina
Docent

James Ritz
Tourist

Felipe Torres Urso
Tourist

Roy Allen III
Cardinal (uncredited)

Victor of Aquitaine
Vatican Choir Member (uncredited)

Michael Ark
CNN Reporter (uncredited)

Sally Berman
Vatican Square Singer (uncredited)

Anthony Bonaventura
Vatican Police (uncredited)

Robert Bradvica
Italian Boy (uncredited)

Ciara Bravo
Italian Girl (uncredited)

Aidan Bristow
Conclave Priest #1 (uncredited)

Raúl Cardona
Piazza Navona Tourist (uncredited)

Pasquale Cassalia
Rai Reporter (uncredited)

Jimmy Clabots
Vatican Choir Member (uncredited)

Austin Michael Coleman
Young Funeral Mourner (uncredited)

Gina D'Acciaro
Vatican Square Singer (uncredited)

William "Will" Daubert
Priest (uncredited)

Vincent De Paul
Vatican Pall Bearer (uncredited)

Norman Deesing
Italian Mourner (uncredited)

Paul DiVito
Priest (uncredited)

William Ferguson
Cardinal (uncredited)

Amanda Jane Fleming
Tourist (uncredited)

Gregory George Frank
Protester (uncredited)

Aaron Denius Garcia
Carabinieri (uncredited)

Justin Giddings
Vatican Choir Member (uncredited)

Phil Gold
Vatican Square Singer (uncredited)

Marco Greco
Fireman (uncredited)

Martin Harris
Polish Reporter (uncredited)

Miriam Harris
Mourner (uncredited)

Charlie Heydt
Swiss Guard (uncredited)

David Hill
Pantheon Tourist (uncredited)

Brett Hunt
Vatican Priest (uncredited)

Marco Infante
Italian Mourner (uncredited)

Christopher Karl Johnson
Cardinal (uncredited)

Gina Juliet
Vatican Square Singer (uncredited)

Slim Khezri
Vatican Square Gypsy (uncredited)

Sophiah Koikas
Tourist (uncredited)

Adrian Lee
Vatican Square Soloist (uncredited)

Maynor Lopez
Carabinieri (uncredited)

Les Mahoney
Hip Priest (uncredited)

Albert Marrero Jr.
News Camerman (uncredited)

Carina Aviles Marshall
Reporter (uncredited)

Sandra McCurdy
Italian Tourist (uncredited)

Anthony Molinari
Vatican Guard (uncredited)

Sauvion Morkunas
Flag-bearer (uncredited)

Dale Pavinski
Carabinieri Captain (uncredited)

Adriana Roze
Vatican Square Singer (uncredited)

Franklin Ruehl
Mourner (uncredited)

Kelly Ryan
Protestor #4 (uncredited)

Dylan Saccoccio
Carabinieri (uncredited)

Frank Scozzari
Vatican Police Officer (uncredited)

James Seaman
Costudi (uncredited)

Jutta Speidel
Woman (uncredited)

Nico Toffoli
Carabieniere Riot (uncredited)

Devin Toft
Carabinieri (uncredited)

James Tumminia
Vatican Priest (uncredited)

Ernie Ventry
Gypsy in Square (uncredited)

Denise Winsor
Vatican Nun (uncredited)

Alfred Molina
Narrator (voice)