Nia Vardalos
Toula Portokalos-Miller

John Corbett
Ian Miller

Elena Kampouris
Paris Miller

Michael Constantine
Kostas "Gus" Portokalos

Lainie Kazan
Maria Portokalos

Andrea Martin
Aunt Voula

Gia Carides
Nikki Portokalos

Joey Fatone
Angelo

Louis Mandylor
Nick Portokalos

Alex Wolff
Bennett

Bruce Gray
Rodney Miller

Fiona Reid
Harriet Miller

Ian Gomez
Mike

Jayne Eastwood
Mrs. White

Rob Riggle
Northwestern Rep

Mark Margolis
Panos

Rita Wilson
Anna

John Stamos
George

Jeanie Calleja
Ilaria

Stavroula Logothettis
Athena

Leonidas Castrounis
Aristotle

Peter Tharos
Yianni

Harper Gunn
Paris at 4

Hershel Blatt
Tommy

Tannis Burnett
Edie

Kathryn Greenwood
Marge

Teresa Pavlinek
Dominique

Aniela Kurylo
Physical Therapist

Sam Moses
Kaveh

Gerry Mendicino
Uncle Taki

Kathryn Haggis
Marianthi

Kolton Stewart
Clifford

Ethan Pugiotto
Theadore

Maria Vacratsis
Aunt Freida

Jeff White
Patrick