Claudia Cardinale
Jill

Henry Fonda
Frank

Jason Robards
'Cheyenne'

Charles Bronson
'Harmonica'

Gabriele Ferzetti
Morton

Paolo Stoppa
Sam

Woody Strode
Frank's Gunman

Jack Elam
Frank's Gunman

Keenan Wynn
Sheriff

Frank Wolff
Brett McBain

Lionel Stander
Innkeeper

Frank Braña
Frank's Gunman (uncredited)

Claudio Mancini
Hanged Man (uncredited)

Al Mulock
Frank's Gunman (uncredited)

Renato Pinciroli
Bidder (uncredited)

Aldo Sambrell
Cheyenne's Gunman (uncredited)

Conrado San Martín
McBain's Neighbor (uncredited)

Enzo Santaniello
Timmy McBain (uncredited)

Fabio Testi
Frank's Gunman (uncredited)

Marco Zuanelli
'Wobbles' (uncredited)

Antonio Molino Rojo
Frank's Gunman (uncredited)

Román Ariznavarreta
Logan (uncredited)

John Frederick
Jim (uncredited)

Aldo Berti
Frank's Gunman (uncredited)

Spartaco Conversi
Frank's Gunman (uncredited)

Saturno Cerra
Frank's Gunman (uncredited)

Paolo Figlia
Frank's Gunman (uncredited)

Dino Mele
Harmonica as a Boy (uncredited)

Simonetta Stefanelli
Maureen McBain (uncredited)

Regina Elena Bisio
Old Woman in the Tavern (uncredited)

Joyce Gordon
Jill McBain (Voice) (Uncredited)

Bernard Grant
Mr. Morton (Voice) (Uncredited)

Dan Sturkie
Wobbles (Voice) (Uncredited)