Dee Bradley Baker
Tippy Toe / Lockjaw (voice)

Chloe Bennet
Daisy Johnson / Quake (voice)

Dove Cameron
Gwen Stacy / Ghost-Spider (voice)

Skai Jackson
Gloria Grant

Kathreen Khavari
Kamala Khan / Ms. Marvel (voice)

Kamil McFadden
Patriot / Rayshaun Lucas (voice)

Bennett Abara
Sheath (voice)

Tyler Posey
Inferno / Dante Pertuz / Newspaper Man (voice)

Cierra Ramirez
America Chavez (voice)

Roger Craig Smith
Captain America / Doreen's Dad / Karl

Booboo Stewart
Exile / Victor Kohl (voice)

Tara Strong
Mary Jane Watson / Automated Voice (voice)

Milana Vayntrub
Squirrel Girl / Doreen Green (voice)

Steven Weber
Captain Stacy / Security Guard (voice)